Globally, overall CVD affects approximately 32.2% of all persons with T2DM. Risk of bias was low 80 ± 12% of STROBE checklist items were adequately addressed. CVD was the cause of death in 9.9% of T2DM patients (representing 50.3% of all deaths). Europe produced the most articles (46%), followed by the Western Pacific/China (21%), and North America (13%). We analyzed data from 57 articles with 4,549,481 persons having T2DM. Risk of bias was examined by applying the STROBE checklist. Two reviewers independently searched for articles and extracted data, adjudicating results through consensus. No restrictions were placed on country of origin or publication language. CVD included stroke, myocardial infarction, angina pectoris, heart failure, ischemic heart disease, cardiovascular disease, coronary heart disease, atherosclerosis, and cardiovascular death. We searched Medline, Embase, and proceedings of major scientific meetings for original research documenting the prevalence of CVD in T2DM.

To estimate the current prevalence of CVD among adults with T2DM by reviewing literature published within the last 10 years (2007–March 2017).

CVD’s prevalence has been growing over time. Cardiovascular disease (CVD) is a common comorbidity in type 2 diabetes (T2DM).

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